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pentobarbital will lower the level or effect of flurbiprofen by influencing hepatic enzyme CYP2C9/10 metabolism. Minimal/Importance Not known.pentobarbital decreases amounts of panobinostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Solid CYP3A4 inducers can minimize panobinostat levels by ~70% and bring about trea